Scientist – MoA (Ref 4204)

March 23, 2021
Permanent

 

With an expanding small molecule drug discovery portfolio Artios Pharma is recruiting for an experienced cell and molecular biologist.  This is an excellent opportunity to join a world class research team in a dynamic, small Biotech company based south of Cambridge, UK.  Artios is focused on identifying and developing cancer treatments by exploiting novel targets within the DNA damage response (DDR), a scientific area of high expectation following the success of PARP inhibitors in the clinic.  The company is actively working on an exciting portfolio of unique DNA repair projects.

 Outline of the role

You will join a growing research team within this innovative and expanding company. Your primary responsibilities will be to support the in vitro pharmacology team in contributing biological data to Artios’ ongoing drug discovery projects. You will achieve this by applying your technical expertise in cell and molecular biology to develop and run mechanistic cell biological studies to understand the mode of action of Artios’ novel anticancer agents. You will also work in multi-disciplinary collaborations with external scientists and leading academics, involving a high level of teamwork.

Qualifications and Experience

Essential

  • PhD or equivalent in a life science subject
  • Minimum of three years’ experience working in a research environment

Desirable

  • Proven track record in the DNA damage response field
  • Experience of in vitro pharmacology or drug discovery
  • Experience working in an industrial setting will be a distinct advantage

 Key Skills and Abilities

 Essential

  • Excellent skills in a broad range of cell and molecular biology techniques including Western blotting, flow cytometry, cell culture and viability assays
  • Specific expertise in mechanistic DNA damage and repair biology and assays such as Comet assays, DNA fibre labelling, cell cycle and repair foci imaging
  • Understanding of basic cancer cell biology
  • Ability to ‘troubleshoot’ experiments independently
  • Ability to work independently as well as part of a team
  • Excellent communication and presentation skills
  • Excellent attention to detail

 Desirable

  • Ability to work independently in an organised and methodical fashion
  • High level of IT literacy
  • Flexible approach to change

This is a permanent position, offering an attractive salary & benefits package. Appointment will be at the Scientist level depending on experience.  If you have the right background, then please apply by sending your CV with a covering letter to hr@artiospharma.com quoting Ref 4204

The closing date is 26 April 2021